There's a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to lessen afferent pain transmission and deliver analgesia. As a result, drugs like clonidine that goal alpha-2 receptors can affect the transmission of soreness. Clonidine is dispersed in breast milk; https://muqtadal379guk7.theideasblog.com/profile